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Nikel, Pablo Ivan (Ed.)ABSTRACT Cultured Myxococcota are predominantly aerobic soil inhabitants, characterized by their highly coordinated predation and cellular differentiation capacities. Little is currently known regarding yet-uncultured Myxococcota from anaerobic, nonsoil habitats. We analyzed genomes representing one novel order (o__JAFGXQ01) and one novel family (f__JAFGIB01) in the Myxococcota from an anoxic freshwater spring (Zodletone Spring) in Oklahoma, USA. Compared to their soil counterparts, anaerobic Myxococcota possess smaller genomes and a smaller number of genes encoding biosynthetic gene clusters (BGCs), peptidases, one- and two-component signal transduction systems, and transcriptional regulators. Detailed analysis of 13 distinct pathways/processes crucial to predation and cellular differentiation revealed severely curtailed machineries, with the notable absence of homologs for key transcription factors (e.g., FruA and MrpC), outer membrane exchange receptor (TraA), and the majority of sporulation-specific and A-motility-specific genes. Further, machine learning approaches based on a set of 634 genes informative of social lifestyle predicted a nonsocial behavior for Zodletone Myxococcota . Metabolically, Zodletone Myxococcota genomes lacked aerobic respiratory capacities but carried genes suggestive of fermentation, dissimilatory nitrite reduction, and dissimilatory sulfate-reduction (in f_JAFGIB01) for energy acquisition. We propose that predation and cellular differentiation represent a niche adaptation strategy that evolved circa 500 million years ago (Mya) in response to the rise of soil as a distinct habitat on Earth. IMPORTANCE The phylum Myxococcota is a phylogenetically coherent bacterial lineage that exhibits unique social traits. Cultured Myxococcota are predominantly aerobic soil-dwelling microorganisms that are capable of predation and fruiting body formation. However, multiple yet-uncultured lineages within the Myxococcota have been encountered in a wide range of nonsoil, predominantly anaerobic habitats, and the metabolic capabilities, physiological preferences, and capacity of social behavior of such lineages remain unclear. Here, we analyzed genomes recovered from a metagenomic analysis of an anoxic freshwater spring in Oklahoma, USA, that represent novel, yet-uncultured, orders and families in the Myxococcota . The genomes appear to lack the characteristic hallmarks for social behavior encountered in Myxococcota genomes and displayed a significantly smaller genome size and a smaller number of genes encoding biosynthetic gene clusters, peptidases, signal transduction systems, and transcriptional regulators. Such perceived lack of social capacity was confirmed through detailed comparative genomic analysis of 13 pathways associated with Myxococcota social behavior, as well as the implementation of machine learning approaches to predict social behavior based on genome composition. Metabolically, these novel Myxococcota are predicted to be strict anaerobes, utilizing fermentation, nitrate reduction, and dissimilarity sulfate reduction for energy acquisition. Our results highlight the broad patterns of metabolic diversity within the yet-uncultured Myxococcota and suggest that the evolution of predation and fruiting body formation in the Myxococcota has occurred in response to soil formation as a distinct habitat on Earth.more » « less
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Abstract Despite the f0(980) hadron having been discovered half a century ago, the question about its quark content has not been settled: it might be an ordinary quark-antiquark ($${{\rm{q}}}\overline{{{\rm{q}}}}$$ ) meson, a tetraquark ($${{\rm{q}}}\overline{{{\rm{q}}}}{{\rm{q}}}\overline{{{\rm{q}}}}$$ ) exotic state, a kaon-antikaon ($${{\rm{K}}}\overline{{{\rm{K}}}}$$ ) molecule, or a quark-antiquark-gluon ($${{\rm{q}}}\overline{{{\rm{q}}}}{{\rm{g}}}$$ ) hybrid. This paper reports strong evidence that the f0(980) state is an ordinary$${{\rm{q}}}\overline{{{\rm{q}}}}$$ meson, inferred from the scaling of elliptic anisotropies (v2) with the number of constituent quarks (nq), as empirically established using conventional hadrons in relativistic heavy ion collisions. The f0(980) state is reconstructed via its dominant decay channel f0(980) →π+π−, in proton-lead collisions recorded by the CMS experiment at the LHC, and itsv2is measured as a function of transverse momentum (pT). It is found that thenq= 2 ($${{\rm{q}}}\overline{{{\rm{q}}}}$$ state) hypothesis is favored overnq= 4 ($${{\rm{q}}}\overline{{{\rm{q}}}}{{\rm{q}}}\overline{{{\rm{q}}}}$$ or$${{\rm{K}}}\overline{{{\rm{K}}}}$$ states) by 7.7, 6.3, or 3.1 standard deviations in thepT< 10, 8, or 6 GeV/cranges, respectively, and overnq= 3 ($${{\rm{q}}}\overline{{{\rm{q}}}}{{\rm{g}}}$$ hybrid state) by 3.5 standard deviations in thepT< 8 GeV/crange. This result represents the first determination of the quark content of the f0(980) state, made possible by using a novel approach, and paves the way for similar studies of other exotic hadron candidates.more » « lessFree, publicly-accessible full text available December 1, 2026
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A first search for beyond the standard model physics in jet multiplicity patterns of multilepton events is presented, using a data sample corresponding to an integrated luminosity of of 13 TeV proton-proton collisions recorded by the CMS detector at the LHC. The search uses observed jet multiplicity distributions in one-, two-, and four-lepton events to explore possible enhancements in jet production rate in three-lepton events with and without bottom quarks. The data are found to be consistent with the standard model expectation. The results are interpreted in terms of supersymmetric production of electroweak chargino-neutralino superpartners with cascade decays terminating in prompt hadronic -parity violating interactions.more » « lessFree, publicly-accessible full text available December 1, 2026
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Free, publicly-accessible full text available September 1, 2026
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Free, publicly-accessible full text available September 1, 2026
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Free, publicly-accessible full text available September 1, 2026
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A search for the rare decay is reported using proton-proton collision events at collected by the CMS detector in 2022–2023, corresponding to an integrated luminosity of . This is the first analysis to use a newly developed inclusive dimuon trigger, expanding the scope of the CMS flavor physics program. The search uses mesons obtained from decays. No significant excess is observed. A limit on the branching fraction of at 95% confidence level is set. This is the most stringent upper limit set on any flavor changing neutral current decay in the charm sector.more » « lessFree, publicly-accessible full text available October 1, 2026
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A<sc>bstract</sc> A search for a heavy pseudoscalar Higgs boson, A, decaying to a 125 GeV Higgs boson h and a Z boson is presented. The h boson is identified via its decay to a pair of tau leptons, while the Z boson is identified via its decay to a pair of electrons or muons. The search targets the production of the A boson via the gluon-gluon fusion process, gg → A, and in association with bottom quarks,$$\text{b}\overline{\text{b}}\text{A }$$. The analysis uses a data sample corresponding to an integrated luminosity of 138 fb−1collected with the CMS detector at the CERN LHC in proton-proton collisions at a centre-of-mass energy of$$\sqrt{s}=13$$TeV. Constraints are set on the product of the cross sections of the A production mechanisms and the A → Zh decay branching fraction. The observed (expected) upper limit at 95% confidence level ranges from 0.049 (0.060) pb to 1.02 (0.79) pb for the gg → A process and from 0.053 (0.059) pb to 0.79 (0.61) pb for the$$\text{b}\overline{\text{b}}\text{A }$$process in the probed range of the A boson mass,mA, from 225 GeV to 1 TeV. The results of the search are used to constrain parameters within the$${\text{M}}_{\text{h},\text{EFT}}^{125}$$benchmark scenario of the minimal supersymmetric extension of the standard model. Values of tanβbelow 2.2 are excluded in this scenario at 95% confidence level for allmAvalues in the range from 225 to 350 GeV.more » « lessFree, publicly-accessible full text available October 1, 2026
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A search for flavor-changing neutral current interactions of the top quark ( ) and the Higgs boson ( ) is presented. The search is based on proton-proton collision data collected in 2016–2018 at a center-of-mass energy of 13 TeV with the CMS detector at the LHC, and corresponding to an integrated luminosity of . Events containing a pair of leptons with the same-sign electric charge and at least one jet are considered. The results are used to constrain the branching fraction ( ) of the top quark decaying to a Higgs boson and an up ( ) or charm ( ) quark. No significant excess above the estimated background was found. The observed (expected) upper limits at a 95% confidence level are found to be 0.072% (0.059%) for and 0.043% (0.062%) for . These results are combined with two other searches performed by the CMS Collaboration for flavor-changing neutral current interactions of top quarks and Higgs bosons in final states where the Higgs boson decays to either a pair of photons or a pair of bottom quarks. The resulting observed (expected) upper limits at the 95% confidence level are 0.019% (0.027%) for and 0.037% (0.035%) for .more » « lessFree, publicly-accessible full text available August 1, 2026
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A<sc>bstract</sc> A search is performed for dark matter (DM) produced in association with a single top quark or a pair of top quarks using the data collected with the CMS detector at the LHC from proton-proton collisions at a center-of-mass energy of 13 TeV, corresponding to 138 fb−1of integrated luminosity. An excess of events with a large imbalance of transverse momentum is searched for across 0, 1 and 2 lepton final states. Novel multivariate techniques are used to take advantage of the differences in kinematic properties between the two DM production mechanisms. No significant deviations with respect to the standard model predictions are observed. The results are interpreted considering a simplified model in which the mediator is either a scalar or pseudoscalar particle and couples to top quarks and to DM fermions. Axion-like particles that are coupled to top quarks and DM fermions are also considered. Expected exclusion limits of 410 and 380 GeV for scalar and pseudoscalar mediator masses, respectively, are set at the 95% confidence level. A DM particle mass of 1 GeV is assumed, with mediator couplings to fermions and DM particles set to unity. A small signal-like excess is observed in data, with the largest local significance observed to be 1.9 standard deviations for the 150 GeV pseudoscalar mediator hypothesis. Because of this excess, mediator masses are only excluded below 310 (320) GeV for the scalar (pseudoscalar) mediator. The results are also translated into model-independent 95% confidence level upper limits on the visible cross section of DM production in association with top quarks, ranging from 1 pb to 0.02 pb.more » « lessFree, publicly-accessible full text available August 1, 2026
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